Think it is best to say that Mayweather, as he has demonstrated, has a great deal of insecurities. IMHO, its best to say, as others have done, that an MMAist or boxer would have advantages in a sporting contest based on the rules they fought under and their own ability. There is not much point in turning this into a style vs. style thread.
"Let your food be your medicine, and your medicine be your food" Hippocrates.