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#380623 - 02/21/08 12:09 AM Re: "KI" effects on cancer cells. Scientific study [Re: wristtwister]
Ed_Morris Offline
Professional Poster

Registered: 11/04/05
Posts: 6768
Quote:

I was merely stating what ran on the news trailer...





sure you were. thats why you added this:
Quote:

Sounds like you need to get back to the lab...




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#380624 - 02/21/08 03:32 AM Re: "KI" effects on cancer cells. Scientific study [Re: Ed_Morris]
ButterflyPalm Offline
Enigma

Registered: 08/26/04
Posts: 2637
Loc: Malaysia
Quote:

BP comments are neither here nor there and not worth addressing. you don't need to be buddies and get to know the person making a privatly-funded study public in order to debate it's method/findings. The guy might also be a war hero, respected church leader or a person on Prozac ...does that change whats in the study or his obvious connection to promotion of a product?




Well, you did say sometime back that you would and will meet up with him, as he claimed to be able to extend his Ki far enough to affect a person at a distance. I was thinking maybe you could meet him and debunk him once and for all, that way this "emotional" Thread can have some measure of "closure"?
_________________________
I'll rather be happy than right, anytime.

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#380625 - 02/21/08 08:59 AM Re: "KI" effects on cancer cells. Scientific study [Re: ButterflyPalm]
Ed_Morris Offline
Professional Poster

Registered: 11/04/05
Posts: 6768
thats correct, but unfortunately after he was made aware of this thread, he has not returned messages or communicated further.

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#380626 - 02/26/08 03:42 AM Re: "KI" effects on cancer cells. Scientific study [Re: ButterflyPalm]
Gavin Offline
Professional Poster

Registered: 05/11/05
Posts: 2267
Loc: Southend, Essex, UK
This see how this one gets twisted to suit everyone's agenda! Have fun:

http://news.bbc.co.uk/1/hi/health/7263494.stm
_________________________
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www.SHIKON.COM
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#380627 - 02/26/08 07:24 AM Re: "KI" effects on cancer cells. Scientific study [Re: Gavin]
Ed_Morris Offline
Professional Poster

Registered: 11/04/05
Posts: 6768
maybe that would be a new thread in the general section, since your link has nothing to do with ki, cancer or martial arts? or even better, make a new thread about placebo itself.

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#380628 - 02/26/08 09:58 AM Re: "KI" effects on cancer cells. Scientific study [Re: Gavin]
Ed_Morris Offline
Professional Poster

Registered: 11/04/05
Posts: 6768
btw, here's the study you refer to: http://medicine.plosjournals.org/perlser...050045&ct=1

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#380629 - 02/29/08 04:34 PM Re: "KI" effects on cancer cells. Scientific study [Re: Ed_Morris]
Vennificus Offline
Member

Registered: 01/21/08
Posts: 206
Loc: The frozen realms of Kah-Nah-D...
For everybody here,
If you had the slightest shred of a chance to help Jonnyboxcutter, regardless of what the masses told you, wouldn't you do everything you could to give him his life back? If someone said, "Hey, I have an Idea, It might help your friend!" would you simply tear it apart and try to prove it wrong, Or, if you could, while he wasn't being treated with regular medicine, would you allow him to be subject to this?
It's a question of ponderance, in case you are wondering, just another thing for you to take as fresh meat.
_________________________
Livestrong Johnnyboxcutter!!

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#380630 - 02/29/08 05:01 PM Re: "KI" effects on cancer cells. Scientific study [Re: Vennificus]
Ed_Morris Offline
Professional Poster

Registered: 11/04/05
Posts: 6768
an attempted low blow. The argument of the study referenced in the opening post has nothing to do with emotions.

not everyone is willing to involk their dying friends/family names in order to make a case. can't do it logically, so play the emotion card?

thats a low functioning argument.

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#380631 - 03/04/08 03:18 PM Re: "KI" effects on cancer cells. Scientific study [Re: Ed_Morris]
Vennificus Offline
Member

Registered: 01/21/08
Posts: 206
Loc: The frozen realms of Kah-Nah-D...
I apoligize.
_________________________
Livestrong Johnnyboxcutter!!

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#380632 - 03/13/08 12:10 AM Re: "KI" effects on cancer cells. Scientific study [Re: Vennificus]
Ed_Morris Offline
Professional Poster

Registered: 11/04/05
Posts: 6768
scientists may have found a real 'Master' that does affect cancer cells:

"Kohwi-Shigematsu's research is part of a new wave of cancer studies focusing on the genetic origins of the disease."
http://news.yahoo.com/s/afp/20080312/ts_afp/healthdiseasecancerbiotechdrugs_080312181303
Quote:


PARIS (AFP) - Geneticists have identified a super gene which causes breast cancer to metastasise, the deadly process by which the disease spreads to other organs, according to a study released Wednesday.

.

Described by the US researchers as a "master regulator," the SATB1 gene alters the behaviour of at least 1,000 other genes within tumour cells, said the study, published in the British journal Nature.

When over-activated it makes cancer cells proliferate, and when neutralised the gene stops the cells from dividing and migrating, the study reported.
.
"SATB1 will be a remarkable target for cancer therapy," lead scientist Termumi Kohwi-Shigematsu of the Lawrence Berkeley National Laboratory in Berkeley, California, told AFP.
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The findings could not only pave the way to diagnostic tools that show the likelihood of the disease spreading, she said, but to drugs that could prevent or treat metastasis in breast cancer as well.
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Up to now, it was impossible to predict whether cancer cells in a tumour were destined to invade neighboring tissue, travel through the blood system and form secondary tumours elsewhere in the body.
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But the SATB1 protein is just such a marker. A tumour in which it is activated "is destined to metastasise," said Kohwi-Shigematsu.
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Metastasis is the overwhelming cause of death in patients with solid tumours. Less than 10 percent of women with metastatic breast cancer survive beyond a decade, and just over a quarter make it past five years.
.
SATB1's normal role in organising other genes -- especially related to T-cells that play a critical role in the immune system -- was already well known, thanks in part to pioneering research by Kohwi-Shigematsu in the 1990s.
.
The gene had also been identified in breast tumours.
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But the new study is the first to establish that "SATB1 is both necessary and sufficient for breast cancer cells to become metastatic," she said.
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In experiments on mice, Kohwi-Shigematsu and colleagues "knocked down", or deactivated, the SATB1 gene by removing certain RNAs in the tumour cells upon which the gene depends for multiplying.
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Messenger RNAs are tiny strings of nucleotides -- the basic building blocks of DNA -- that ferry the blueprints for constructing proteins from DNA genes to the cell's ribosomes, the factories where proteins are made.
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The results, compared to control mice also infected with human metastatic breast cancer cells, were dramatic.
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Between 125 and 160 metastatic nodules formed in each lung of all the control mice. But in the rodents in which SATB1 was suppressed, the number was between zero and five.
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Deliberately over-expressing the gene had the opposite effect, causing the cancer cells to rapidly reproduce and run amok.
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Translating the study's findings into an effective treatment for cancer would require targeting only the tumours in which the SATB1 gene has become overly active.
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A drug that blocked the gene throughout the body would compromise its critical -- and normal -- role in activating the immune system.
.
Kohwi-Shigematsu is working on a means for delivering an inhibitor via microscopic nanocapsules, and said trials on humans could start within a couple of years. Prognostic tools could be available within a year.
.
Kohwi-Shigematsu's research is part of a new wave of cancer studies focusing on the genetic origins of the disease.
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Scientists have come to realise, she said, that there are gene expression patterns called prognosis signatures, genetic profiles found across primary tumours that have metastatic potential.
.
"And now we have identified the protein master regulator for metastatis," she said.
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But the most basic question remains to be answered, she added. "What turns SATB1 on during the course of breast cancer progression? We just don't know."
.
According to the American Cancer Society, about 1.3 million women worldwide are diagnosed each year with breast cancer, and nearly half-a-million succumb to the disease.





Looks like promising research. seems being honest with what they don't know leads to the pursuit of finding out.

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