From a personal standpoint as a security officer, I wear slash resistant gloves to minimise injury if caught up in a bladed encounter- it would (in theory) give me a little leeway to grab/trap the knife itself as oposed to worrying about getting past it to the controlling arm.
My father was in L.E. for close to 30 years, and has always said if a fellon uses his open hands, use your baton, if they have any weapon, be it oppertunistic or premeditated, Draw your sidearm to either take controll through coersion and to ensure their compliance , or if need be to shoot the SOB and remove the threat.